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Immune Dysregulation as a Cause of Autoinflammation in Fragile X Premutation Carriers: Link between FMRI CGG Repeat Number and Decreased Cytokine Responses

BACKGROUND: Increased rates of autoinflammatory and autoimmune disorders have been observed in female premutation carriers of CGG repeat expansion alleles of between 55–200 repeats in the fragile X mental retardation 1 (FMR1) gene. To determine whether an abnormal immune profile was present at a cel...

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Detalhes bibliográficos
Main Authors: Careaga, Milo, Rose, Destanie, Tassone, Flora, Berman, Robert F., Hagerman, Randi, Ashwood, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981824/
https://ncbi.nlm.nih.gov/pubmed/24718368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094475
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