Translational Signalling, Atrogenic and Myogenic Gene Expression during Unloading and Reloading of Skeletal Muscle in Myostatin-Deficient Mice

Skeletal muscles of myostatin null (Mstn(−/−)) mice are more susceptible to atrophy during hind limb suspension (HS) than are muscles of wild-type mice. Here we sought to elucidate the mechanism for this susceptibility and to determine if Mstn(−/−) mice can regain muscle mass after HS. Male Mstn(−/−...

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Main Authors: Smith, Heather K., Matthews, Kenneth G., Oldham, Jenny M., Jeanplong, Ferenc, Falconer, Shelley J., Bass, James J., Senna-Salerno, Mônica, Bracegirdle, Jeremy W., McMahon, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981781/
https://ncbi.nlm.nih.gov/pubmed/24718581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094356
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