The allele-specific synthetic lethality of prlA-prlG double mutants predicts interactive domains of SecY and SecE.

The secretion of proteins from the cytoplasm of Escherichia coli requires the interaction of two integral inner membrane components, SecY and SecE. We have devised a genetic approach to probe the molecular nature of the SecY-SecE interaction. Suppressor alleles of secY and secE, termed prlA and prlG...

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Pubblicato in:	EMBO J
Autori principali:	Flower, A M, Osborne, R S, Silhavy, T J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398161/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7889938/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07070.x
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