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Evidence for a Prp24 binding site in U6 snRNA and in a putative intermediate in the annealing of U6 and U4 snRNAs.

A mutation (U4-G14C) that destabilizes the base-pairing interaction between U4 and U6 snRNAs causes the accumulation of a novel complex containing U4, U6 and Prp24, a protein with RNA binding motifs. An analysis of suppressors of this cold-sensitive mutant led to the hypothesis that this complex is...

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Bibliografische gegevens
Hoofdauteurs: Jandrositz, A, Guthrie, C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC398149/
https://ncbi.nlm.nih.gov/pubmed/7882985
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