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Targeting gene expression to haemopoietic stem cells: a chromatin-dependent upstream element mediates cell type-specific expression of the stem cell antigen CD34.

The ability to target heterologous gene expression to haemopoietic stem cells will allow biological manipulation of this compartment and facilitate gene therapy of blood disorders. To identify regulatory elements with this potential, we have analysed the transcriptional regulation of the murine stem...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: May, G, Enver, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398115/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7532132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07032.x
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