Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice.

Gene transduction of pluripotent human hematopoietic stem cells (HSCs) is necessary for successful gene therapy of genetic disorders involving hematolymphoid cells. Evidence for transduction of pluripotent HSCs can be deduced from the demonstration of a retroviral vector integrated into the same cel...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Nolta, J A, Dao, M A, Wells, S, Smogorzewska, E M, Kohn, D B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39811/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8637888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.6.2414
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