Nucleosome sliding by Chd1 does not require rigid coupling between DNA-binding and ATPase domains

Chromatin remodellers are ATP-dependent motor proteins that physically reposition and reorganize nucleosomes. Chd1 and Iswi-type remodellers possess a DNA-binding domain (DBD) needed for efficient nucleosome mobilization; however, it has not been clear how this domain physically contributes to remod...

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Bibliographic Details
Main Authors: Nodelman, Ilana M, Bowman, Gregory D
Format: Artigo
Language:Inglês
Published: European Molecular Biology Organization 2013
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981083/
https://ncbi.nlm.nih.gov/pubmed/24126763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.158
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