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Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor.

Induction of apoptosis in lymphocytes, which may account for the therapeutic effects of glucocorticoids in various diseases including leukemia, depends on the glucocorticoid receptor. However, the events leading from the activated receptor to cell lysis are not understood. A prevailing hypothesis po...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Helmberg, A, Auphan, N, Caelles, C, Karin, M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398103/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7859735/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07021.x
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