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Effects of secondary structure on pre-mRNA splicing: hairpins sequestering the 5' but not the 3' splice site inhibit intron processing in Nicotiana plumbaginifolia.

We have performed a systematic study of the effect of artificial hairpins on pre-mRNA splicing in protoplasts of a dicot plant, Nicotiana plumbaginifolia. Hairpins with a potential to form 18 or 24 bp stems strongly inhibit splicing when they sequester the 5' splice site or are placed in the middle...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Liu, H X, Goodall, G J, Kole, R, Filipowicz, W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7835348/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07012.x
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