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Brain capillary endothelium and choroid plexus epithelium regulate transport of transferrin-bound and free iron into the rat brain

Iron transport into the CNS is still not completely understood. Using a brain perfusion technique in rats, we have shown a significant brain capillary uptake of circulating transferrin (Tf)-bound and free (59)Fe (1 nM) at rates of 136 ± 26 and 182 ± 23 μL/g/min, respectively, while their respective...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deane, Rashid, Zheng, Wei, Zlokovic, Berislav V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980859/
https://ncbi.nlm.nih.gov/pubmed/14756801
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