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Heme binds to a short sequence that serves a regulatory function in diverse proteins.

Heme is a prosthetic group for numerous enzymes, cytochromes and globins, and it binds tightly, sometimes covalently, to these proteins. Interestingly, heme also potentiates binding of the yeast transcriptional activator HAP1 to DNA and inhibits mitochondrial import of the mammalian delta-aminolevul...

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Autors principals: Zhang, L, Guarente, L
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC398085/
https://ncbi.nlm.nih.gov/pubmed/7835342
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