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A metabolomics investigation of non genotoxic carcinogenicity in the rat

Non-genotoxic carcinogens (NGCs) promote tumour growth by altering gene expression which ultimately leads to cancer without directly causing a change in DNA sequence. As a result NGCs are not detected in mutagenesis assays. Whilst there are proposed biomarkers of carcinogenic potential, the definiti...

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Detalhes bibliográficos
Main Authors: Ament, Zsuzsanna, Waterman, Claire L, West, James A, Waterfield, Catherine, Currie, Richard A, Wright, Jayne, Griffin, Julian L
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980845/
https://ncbi.nlm.nih.gov/pubmed/24161236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr4007766
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