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Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation.

Activation of the membrane fusion potential of influenza haemagglutinin (HA) at endosomal pH requires changes in its structure. X-ray analysis of TBHA2, a proteolytic fragment of HA in the fusion pH conformation, indicates that at the pH of fusion the 'fusion peptide' is displaced by > 10 nm from it...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Wharton, S A, Calder, L J, Ruigrok, R W, Skehel, J J, Steinhauer, D A, Wiley, D C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7835335/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb06997.x
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