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Reduced aerobic capacity causes leaky ryanodine receptors that trigger arrhythmia in a rat strain artificially selected and bred for low aerobic running capacity

AIM: Rats selectively bred for inborn Low Capacity of Running (LCR) display a series of poor health indices where as rats selected for High Capacity of Running (HCR) display a healthy profile. We hypothesized that selection of low aerobic capacity over generations leads to a phenotype with increased...

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Detalhes bibliográficos
Main Authors: Høydal, MA, Stølen, TO, Johnsen, AB, Alvez, M, Catalucci, D, Condorelli, G, Koch, LG, Britton, SL, Smith, GL, Wisløff, U
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980721/
https://ncbi.nlm.nih.gov/pubmed/24444142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12238
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