B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2.

Infection of primary B-lymphocytes by Epstein-Barr virus (EBV) leads to growth transformation of these B-cells in vitro. EBV nuclear antigen 2 (EBNA2), one of the first genes expressed after EBV infection of B-cells, is a transcriptional activator of viral and cellular genes and is essential for the...

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Publicado en:EMBO J
Autores principales: Kempkes, B, Spitkovsky, D, Jansen-Dürr, P, Ellwart, J W, Kremmer, E, Delecluse, H J, Rottenberger, C, Bornkamm, G W, Hammerschmidt, W
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398055/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7828599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb06978.x
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