Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.

We have monitored L-type Ca2+ channel activity, local cytoplasmic Ca2+ transients, the distribution of insulin-containing secretory granules and exocytosis in individual mouse pancreatic B-cells. Subsequent to the opening of the Ca2+ channels, exocytosis is initiated with a latency < 100 ms. The ent...

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Detalles Bibliográficos

Publicado en:	EMBO J
Principais autores:	Bokvist, K, Eliasson, L, Ammälä, C, Renström, E, Rorsman, P
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398051/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7828595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb06974.x
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