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Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations

The distribution of mutational fitness effects (DMFE) is crucial to the evolutionary fate of quasispecies. In this article we analyze the effect of the DMFE on the dynamics of a large quasispecies by means of a phenotypic version of the classic Eigen's model that incorporates beneficial, neutra...

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Detalhes bibliográficos
Main Authors: Sardanyés, Josep, Simó, Carles, Martínez, Regina, Solé, Ricard V., Elena, Santiago F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980229/
https://ncbi.nlm.nih.gov/pubmed/24713667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04625
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