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The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines

In response to ionizing radiation, several signaling cascades in the cell are activated to repair the DNA breaks, prevent apoptosis, and keep the cells proliferating. AKT is important for survival and proliferation and may also be an activating factor for DNA-PKcs and MRE11, which are essential prot...

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Bibliografiske detaljer
Main Authors: Sahlberg, Sara Häggblad, Gustafsson, Ann-Sofie, Pendekanti, Prathyusha N., Glimelius, Bengt, Stenerlöw, Bo
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980041/
https://ncbi.nlm.nih.gov/pubmed/24338765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-013-1465-9
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