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Defining Presynaptic Nicotinic Receptors Regulated by Beta Amyloid in Mouse Cortex and Hippocampus with Receptor Null Mutants

Disruption of neuronal signaling by soluble β-amyloid has been implicated in deficits in short-term recall in the early stages of Alzheimer's disease. One potential target for β-amyloid is the synapse, with evidence for differential interaction with both pre- and postsynaptic elements. Our prev...

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Detalhes bibliográficos
Main Authors: Mehta, Tejal K., Dougherty, John J., Wu, Jianlin, Choi, Catherine H., Khan, Ghous M., Nichols, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979963/
https://ncbi.nlm.nih.gov/pubmed/19457164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06070.x
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