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Autoregulation of lin-4 microRNA transcription by RNA activation (RNAa) in C. elegans

The conserved lin-4 microRNA (miRNA) regulates the proper timing of stem cell fate decisions in C. elegans by regulating stemness genes such as lin-14 and lin-28.(1)(-)(3) While lin-4 is upregulated toward the end of the first larval stage and functions as an essential developmental timing “switch”,...

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Detalhes bibliográficos
Main Authors: Turner, Michael J, Jiao, Alan L, Slack, Frank J
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979913/
https://ncbi.nlm.nih.gov/pubmed/24398561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27679
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