Inhibition of stearoyl-coA desaturase selectively eliminates tumorigenic Nanog-positive cells: Improving the safety of iPS cell transplantation to myocardium

Induced pluripotent stem cells (iPS) can differentiate into cardiomyocytes (CM) and represent a promising form of cellular therapy for heart regeneration. However, residual undifferentiated iPS derivates (iPSD), which are not fully eliminated by cell differentiation or purification protocols, may fo...

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Main Authors: Zhang, Lan, Pan, Yaohua, Qin, Gangjian, Chen, Lijuan, Chatterjee, Tapan K, Weintraub, Neal L, Tang, Yaoliang
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979912/
https://ncbi.nlm.nih.gov/pubmed/24394703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27677
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