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Enhanced Production of Chikungunya Virus-Like Particles Using a High-pH Adapted Spodoptera frugiperda Insect Cell Line
Chikungunya virus-like particles (VLPs) have potential to be used as a prophylactic vaccine based on testing in multiple animal models and are currently being evaluated for human use in a Phase I clinical trial. The current method for producing these enveloped alphavirus VLPs by transient gene expre...
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Main Authors: | , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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Public Library of Science
2014
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979839/ https://ncbi.nlm.nih.gov/pubmed/24713807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094401 |
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