Involvement of the Akt/NF-κB Pathways in the HTNV-Mediated Increase of IL-6, CCL5, ICAM-1, and VCAM-1 in HUVECs

BACKGROUND: Hantaan virus (HTNV) infection causes a severe form of HFRS(hemorrhagic fever with renal syndrome)in Asia. Although HTNV has been isolated for nearly forty years, the pathogenesis of HFRS is still unknown, and little is known regarding the signaling pathway that is activated by the virus...

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Detalhes bibliográficos
Main Authors: Yu, Haitao, Jiang, Wei, Du, Hong, Xing, Yuan, Bai, Guangzhen, Zhang, Ye, Li, Yu, Jiang, Hong, Zhang, Ying, Wang, Jiuping, Wang, Pingzhong, Bai, Xuefan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979720/
https://ncbi.nlm.nih.gov/pubmed/24714064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093810
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