Involvement of the Akt/NF-κB Pathways in the HTNV-Mediated Increase of IL-6, CCL5, ICAM-1, and VCAM-1 in HUVECs

BACKGROUND: Hantaan virus (HTNV) infection causes a severe form of HFRS(hemorrhagic fever with renal syndrome)in Asia. Although HTNV has been isolated for nearly forty years, the pathogenesis of HFRS is still unknown, and little is known regarding the signaling pathway that is activated by the virus...

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Autors principals: Yu, Haitao, Jiang, Wei, Du, Hong, Xing, Yuan, Bai, Guangzhen, Zhang, Ye, Li, Yu, Jiang, Hong, Zhang, Ying, Wang, Jiuping, Wang, Pingzhong, Bai, Xuefan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979720/
https://ncbi.nlm.nih.gov/pubmed/24714064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093810
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