Vasoreparative Dysfunction of CD34(+) Cells in Diabetic Individuals Involves Hypoxic Desensitization and Impaired Autocrine/Paracrine Mechanisms

We hypothesized that endothelial progenitor cells derived from individuals with diabetes would exhibit functional defects including inability to respond to hypoxia and altered paracrine/autocrine function that would impair the angiogenic potential of these cells. Circulating mononuclear cells isolat...

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Detalhes bibliográficos
Main Authors: Jarajapu, Yagna P. R., Hazra, Sugata, Segal, Mark, LiCalzi, Sergio, Jhadao, Chandra, Qian, Kevin, Mitter, Sayak K., Raizada, Mohan K., Boulton, Michael E., Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979711/
https://ncbi.nlm.nih.gov/pubmed/24713821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093965
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