Mapping of the C3d receptor (CR2)-binding site and a neoantigenic site in the C3d domain of the third component of complement.

The C3d domain of C3 contains the site that binds to the C3d receptor (CR2) which is expressed on B lymphocytes. It also contains a neoantigenic determinant that is recognized by monoclonal antibody (mAb) 130 and is expressed when C3b is cleaved to iC3b and subsequently to C3dg or C3d. mAb 130 inhib...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lambris, J D, Ganu, V S, Hirani, S, Müller-Eberhard, H J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2408276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.12.4235
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