A Model-Based Approach to Identify Binding Sites in CLIP-Seq Data

Cross-linking immunoprecipitation coupled with high-throughput sequencing (CLIP-Seq) has made it possible to identify the targeting sites of RNA-binding proteins in various cell culture systems and tissue types on a genome-wide scale. Here we present a novel model-based approach (MiClip) to identify...

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Bibliographic Details
Main Authors: Wang, Tao, Chen, Beibei, Kim, MinSoo, Xie, Yang, Xiao, Guanghua
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979666/
https://ncbi.nlm.nih.gov/pubmed/24714572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093248
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