CD4CD8αα Lymphocytes, A Novel Human Regulatory T Cell Subset Induced by Colonic Bacteria and Deficient in Patients with Inflammatory Bowel Disease

How the microbiota affects health and disease is a crucial question. In mice, gut Clostridium bacteria are potent inducers of colonic interleukin (IL)-10-producing Foxp3 regulatory T cells (Treg), which play key roles in the prevention of colitis and in systemic immunity. In humans, although gut mic...

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Detalhes bibliográficos
Main Authors: Sarrabayrouse, Guillaume, Bossard, Céline, Chauvin, Joe-Marc, Jarry, Anne, Meurette, Guillaume, Quévrain, Elodie, Bridonneau, Chantal, Preisser, Laurence, Asehnoune, Karim, Labarrière, Nathalie, Altare, Frédéric, Sokol, Harry, Jotereau, Francine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979654/
https://ncbi.nlm.nih.gov/pubmed/24714093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001833
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