Genetic evidence that the RAG1 protein directly participates in V(D)J recombination through substrate recognition.
RAG1 protein is essential for the activation of V(D)J recombination in developing lymphocytes (V, variable; D, diversity; J, joining). However, it has not been determined whether its role involves substrate recognition and catalysis. A single amino acid substitution mutation in the RAG1 gene has now...
Spremljeno u:
| Izdano u: | Proc Natl Acad Sci U S A |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1996
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39796/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8637873/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.6.2333 |
| Oznake: |
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|