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Triiodothyronine induces hepatocyte proliferation by Protein Kinase A-Dependent β-Catenin Activation in Rodents

Thyroid hormone (T3), like many other ligands of the steroid/thyroid hormone nuclear receptor superfamily is a strong inducer of liver cell proliferation in rats and mice. However, the molecular basis of its mitogenic activity, which is currently unknown, must be elucidated if its use in hepatic reg...

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Detalhes bibliográficos
Main Authors: Fanti, Maura, Singh, Sucha, Ledda-Columbano, Giovanna M, Columbano, Amedeo, Monga, Satdarshan P
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979513/
https://ncbi.nlm.nih.gov/pubmed/24122933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26775
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