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Stimulation of in vitro human skin collagenase expression by platelet-derived growth factor.

Platelet-derived growth factor (PDGF) is both chemoattractant and mitogenic for stromal cells. Here, we examined the effects of PDGF on collagenase expression by normal human skin fibroblasts. Culturing cells for 24 hr in the presence of PDGF at 0-180 ng/ml resulted in a dose-dependent, saturable in...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bauer, E A, Cooper, T W, Huang, J S, Altman, J, Deuel, T F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397949/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2987965/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.12.4132
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