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ACE inhibition enhances bradykinin relaxations through nitric oxide and B1 receptor activation in bovine coronary arteries

Bradykinin causes vascular relaxations through release of endothelial relaxing factors including prostacyclin, nitric oxide (NO) and epoxyeicosatrienoic acids (EETs). Bradykinin is metabolized by angiotensin converting enzyme (ACE) and ACE inhibition enhances bradykinin relaxations. Our goal was to...

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Detalhes bibliográficos
Main Authors: Gauthier, Kathryn M., Cepura, Cody J., Campbell, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979287/
https://ncbi.nlm.nih.gov/pubmed/23729620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2012-0348
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