Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior

Two genome duplications early in the vertebrate lineage expanded gene families including GluN2 subunits of the NMDA receptor. Diversification between the four mammalian GluN2 proteins occurred primarily at their intracellular C-terminal domains (CTDs). To identify shared ancestral functions and dive...

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Bibliografiska uppgifter
Huvudupphovsmän: Ryan, Tomás J., Kopanitsa, Maksym V., Indersmitten, Tim, Nithianantharajah, Jess, Afinowi, Nurudeen O., Pettit, Charles, Stanford, Lianne E., Sprengel, Rolf, Saksida, Lisa M., Bussey, Timothy J., O’Dell, Thomas J., Grant, Seth G. N., Komiyama, Noboru H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979286/
https://ncbi.nlm.nih.gov/pubmed/23201971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3277
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