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Annotating N Termini for the Human Proteome Project: N Termini and Nα-Acetylation Status Differentiate Stable Cleaved Protein Species from Degradation Remnants in the Human Erythrocyte Proteome

[Image: see text] A goal of the Chromosome-centric Human Proteome Project is to identify all human protein species. With 3844 proteins annotated as “missing”, this is challenging. Moreover, proteolytic processing generates new protein species with characteristic neo-N termini that are frequently acc...

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Detalhes bibliográficos
Main Authors: Lange, Philipp F., Huesgen, Pitter F., Nguyen, Karen, Overall, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979129/
https://ncbi.nlm.nih.gov/pubmed/24555563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr401191w
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