A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 trans-signaling in a murine model

INTRODUCTION: Tumor cell interactions with the microenvironment, especially those of bone-marrow-derived myeloid cells, are important in various aspects of tumor metastasis. Myeloid-derived suppressor cells (MDSCs) have been suggested to constitute tumor-favoring microenvironments. In this study, we...

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Detalhes bibliográficos
Main Authors: Oh, Keunhee, Lee, Ok-Young, Shon, Suh Youn, Nam, Onyou, Ryu, Po Mee, Seo, Myung Won, Lee, Dong-Sup
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979084/
https://ncbi.nlm.nih.gov/pubmed/24021059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3473
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