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Adenosine-to-inosine RNA editing and human disease

A-to-I RNA editing is a post-transcriptional modification that converts adenosines to inosines in both coding and noncoding RNA transcripts. It is catalyzed by ADAR (adenosine deaminase acting on RNA) enzymes, which exist throughout the body but are most prevalent in the central nervous system. Inos...

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Detalhes bibliográficos
Main Authors: Slotkin, William, Nishikura, Kazuko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979043/
https://ncbi.nlm.nih.gov/pubmed/24289319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm508
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