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Adenosine-to-inosine RNA editing and human disease

A-to-I RNA editing is a post-transcriptional modification that converts adenosines to inosines in both coding and noncoding RNA transcripts. It is catalyzed by ADAR (adenosine deaminase acting on RNA) enzymes, which exist throughout the body but are most prevalent in the central nervous system. Inos...

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Bibliografiske detaljer
Main Authors: Slotkin, William, Nishikura, Kazuko
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979043/
https://ncbi.nlm.nih.gov/pubmed/24289319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm508
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