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NK4 therapy: a new approach to target angiogenesis and inflammation in rheumatoid arthritis
Rheumatoid arthritis (RA) is a progressive autoimmune disease characterized by synovial membrane hyperplasia, inflammation, and angiogenesis. Hepatocyte growth factor (HGF) and its receptor, c-Met, are both overexpressed in the RA synovium. NK4 is an antagonist of HGF which has been shown to inhibit...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979028/ https://ncbi.nlm.nih.gov/pubmed/24074223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4320 |
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