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LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling

INTRODUCTION: Lysyl oxidase-like 2 (LOXL2) is a matrix-remodeling enzyme that has been shown to play a key role in invasion and metastasis of breast carcinoma cells. However, very little is known about its role in normal tissue homeostasis. Here, we investigated the effects of LOXL2 expression in no...

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Détails bibliographiques
Auteurs principaux: Chang, Joan, Nicolau, Monica M, Cox, Thomas R, Wetterskog, Daniel, Martens, John WM, E Barker, Holly, Erler, Janine T
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978831/
https://ncbi.nlm.nih.gov/pubmed/23971878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3461
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