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LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling

INTRODUCTION: Lysyl oxidase-like 2 (LOXL2) is a matrix-remodeling enzyme that has been shown to play a key role in invasion and metastasis of breast carcinoma cells. However, very little is known about its role in normal tissue homeostasis. Here, we investigated the effects of LOXL2 expression in no...

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Autori principali: Chang, Joan, Nicolau, Monica M, Cox, Thomas R, Wetterskog, Daniel, Martens, John WM, E Barker, Holly, Erler, Janine T
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978831/
https://ncbi.nlm.nih.gov/pubmed/23971878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3461
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