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The C1q subunit of the first component of complement binds to laminin: a mechanism for the deposition and retention of immune complexes in basement membrane.

The C1q subunit of complement component C1 is known to bind to immune complexes, which often are deposited in basement membrane. We investigated the possibility that this deposition is a result of binding to laminin, a large basement membrane glycoprotein. C1q showed saturable binding to immobilized...

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Autori principali: Bohnsack, J F, Tenner, A J, Laurie, G W, Kleinman, H K, Martin, G R, Brown, E J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC397880/
https://ncbi.nlm.nih.gov/pubmed/2987948
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