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Specific 5' and 3' regions of the mu-chain gene are undermethylated at distinct stages of B-cell differentiation.

The mu-chain gene is expressed differently in successive stages of B-lymphocyte development. The heavy chain product appears as a cytoplasmic constituent in pre-B-cells, as part of the IgM receptor in maturing B cells, and as a component in the pentamer IgM antibody synthesized and secreted by the a...

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Detalhes bibliográficos
Main Authors: Blackman, M A, Koshland, M E
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC397877/
https://ncbi.nlm.nih.gov/pubmed/2582426
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