PDL241, a novel humanized monoclonal antibody, reveals CD319 as a therapeutic target for rheumatoid arthritis

INTRODUCTION: Targeting the CD20 antigen has been a successful therapeutic intervention in the treatment of rheumatoid arthritis (RA). However, in some patients with an inadequate response to anti-CD20 therapy, a persistence of CD20(-) plasmablasts is noted. The strong expression of CD319 on CD20(-)...

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Detalhes bibliográficos
Main Authors: Woo, Jacky, Vierboom, Michel PM, Kwon, Hakju, Chao, Debra, Ye, Shiming, Li, Jianmin, Lin, Karen, Tang, Irene, Belmar, Nicole A, Hartman, Taymar, Breedveld, Elia, Vexler, Vladimir, ‘t Hart, Bert A, Law, Debbie A, Starling, Gary C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978732/
https://ncbi.nlm.nih.gov/pubmed/24299175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4400
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