PIK3CA mutations are frequently observed in BRCAX but not BRCA2 -associated male breast cancer

INTRODUCTION: Although a substantial proportion of male breast cancers (MBCs) are hereditary, the molecular pathways that are activated are unknown. We therefore examined the frequency and clinicopathological associations of the PIK3CA/mammalian target of rapamycin (mTOR) and mitogen-activated prote...

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Bibliographic Details
Main Authors: Deb, Siddhartha, Do, Hongdo, Byrne, David, Jene, Nicholas, Dobrovic, Alexander, Fox, Stephen B
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978692/
https://ncbi.nlm.nih.gov/pubmed/23971979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3463
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