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Fusion of a Short HA2-Derived Peptide Sequence to Cell-Penetrating Peptides Improves Cytosolic Uptake, but Enhances Cytotoxic Activity

Cell-penetrating peptides (CPP) have become a widely used tool for efficient cargo delivery into cells. However, one limiting fact is their uptake by endocytosis causing the enclosure of the CPP-cargo construct within endosomes. One often used method to enhance the outflow into the cytosol is the fu...

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Autors principals: Neundorf, Ines, Rennert, Robert, Hoyer, Jan, Schramm, Franziska, Löbner, Kristin, Kitanovic, Igor, Wölfl, Stefan
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978507/
https://ncbi.nlm.nih.gov/pubmed/27713223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph2020049
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