Smoking in combination with antibodies to cyclic citrullinated peptides is associated with persistently high levels of survivin in early rheumatoid arthritis: a prospective cohort study

INTRODUCTION: High levels of the oncoprotein survivin may be detected in the majority of patients with early rheumatoid arthritis (RA). Survivin is a sensitive predictor of joint damage and persistent disease activity. Survivin-positive patients are often poor responders to antirheumatic and biologi...

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Bibliographic Details
Main Authors: Svensson, Björn, Hafström, Ingiäld, Erlandsson, Malin C, Forslind, Kristina, Bokarewa, Maria I
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978453/
https://ncbi.nlm.nih.gov/pubmed/24428870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4438
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