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Cancer mutation signatures, DNA damage mechanisms, and potential clinical implications

Knowledge of cancer genomic DNA sequences has created unprecedented opportunities for mutation studies. Computational analyses have begun to decipher mutational signatures that identify underlying causes. A recent analysis encompassing 30 cancer types reported 20 distinct mutation signatures, result...

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Détails bibliographiques
Auteur principal: Harris, Reuben S
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978439/
https://ncbi.nlm.nih.gov/pubmed/24073723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm490
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