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Reducing the noise in signal detection of adverse drug reactions by standardizing the background: a pilot study on analyses of proportional reporting ratios-by-therapeutic area

PURPOSE: Disproportionality screening analysis is acknowledged as a tool for performing signal detection in databases of adverse drug reactions (ADRs), e.g., in the European Union (EU) Drug Authority setting. The purpose of this study was to explore the possibility of decreasing false-positive signa...

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Detalhes bibliográficos
Main Authors: Grundmark, Birgitta, Holmberg, Lars, Garmo, Hans, Zethelius, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978377/
https://ncbi.nlm.nih.gov/pubmed/24599513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-014-1658-1
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