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Motifs in the permeation pathway of connexin channels mediate voltage and Ca(2+) sensing
Connexin channels mediate electrical coupling, intercellular molecular signaling, and extracellular release of signaling molecules. Connexin proteins assemble intracellularly as hexamers to form plasma membrane hemichannels. The docking of two hemichannels in apposed cells forms a gap junction chann...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978323/ https://ncbi.nlm.nih.gov/pubmed/24744733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00113 |
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