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A monoclonal antibody against human thrombospondin inhibits platelet aggregation.

A monoclonal antibody (C6.7) has been generated against the calcium-replete form of human platelet thrombospondin (TSP). C6.7 is specific for TSP as determined by both competitive radioimmunoassay and immunoprecipitation. This antibody inhibits both thrombin- and A23187-induced aggregation of gel-fi...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Dixit, V M, Haverstick, D M, O'Rourke, K M, Hennessy, S W, Grant, G A, Santoro, S A, Frazier, W A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1985
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397798/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2582413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3472
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