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Focal smooth muscle proliferation in the aortic intima produced by an initiation-promotion sequence.

Human atherosclerotic fibrous plaques display a clonal character similar to many benign neoplasms. We report here that chickens treated with an initiation-promotion sequence developed focal intimal smooth muscle lesions in the thoracic aorta that resemble early forms of atherosclerosis. Scanning ele...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Majesky, M W, Reidy, M A, Benditt, E P, Juchau, M R
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1985
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3923478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3450
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