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Suppression of Graft Regeneration, Not Ischemia/Reperfusion Injury, Is the Primary Cause of Small-for-Size Syndrome after Partial Liver Transplantation in Mice

BACKGROUND: Ischemia/reperfusion injury (IRI) is commonly considered to play a crucial role in the pathogenesis of small-for-size syndrome (SFSS) after liver transplantation. Rapid regeneration is also considered essential for the survival of SFS grafts. METHODS: Mouse models of full-size orthotopic...

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Detalhes bibliográficos
Main Authors: Pan, Ning, Lv, Xiangwei, Liang, Rui, Wang, Liming, Liu, Qinlong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977924/
https://ncbi.nlm.nih.gov/pubmed/24709852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093636
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