Beneficial Metabolic Effects of Rapamycin Are Associated with Enhanced Regulatory Cells in Diet-Induced Obese Mice

The “mechanistic target of rapamycin” (mTOR) is a central controller of growth, proliferation and/or motility of various cell-types ranging from adipocytes to immune cells, thereby linking metabolism and immunity. mTOR signaling is overactivated in obesity, promoting inflammation and insulin resista...

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Detalhes bibliográficos
Main Authors: Makki, Kassem, Taront, Solenne, Molendi-Coste, Olivier, Bouchaert, Emmanuel, Neve, Bernadette, Eury, Elodie, Lobbens, Stéphane, Labalette, Myriam, Duez, Hélène, Staels, Bart, Dombrowicz, David, Froguel, Philippe, Wolowczuk, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977858/
https://ncbi.nlm.nih.gov/pubmed/24710396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092684
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